Wegener's Granulomatosis Presenting with Diffuse Alveolar Hemorrhage and Negative Antineutrophilic Cytoplasmic Antibody Test
نویسندگان
چکیده
منابع مشابه
Granulomatosis with polyangiitis presenting with diffuse alveolar hemorrhage requiring extracorporeal membrane oxygenation with rapid multiorgan relapse
RATIONALE Granulomatosis with polyangiitis (GPA) is an antineutrophil cytoplasmatic antibodies (ANCA)-associated vasculitis affecting small- and medium-sized blood vessels, mostly involving lung and kidney. PATIENT CONCERNS We report the case of a 33-year-old man that presented with acute respiratory distress syndrome caused by alveolar hemorrhage. DIAGNOSES Aggressive GPA presenting with d...
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Propylthiouracil (PTU) is known to be a potential cause of antineutrophil cytoplasmic antibody (ANCA) positive small vessel vasculitis, resulting in glomerulonephritis and diffuse alveolar hemorrhage (DAH). Herein, we describe a 25-year-old pregnant woman who developed a perinulcear ANCA (p-ANCA) and myeloperoxidase ANCA (MPO-ANCA) positive DAH during PTU therapy. The patient improved after cor...
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Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical intravascular hemolytic anemia with schistocytosis, thrombocytopenia and acute renal failure. Pulmonary involvement in HUS is known to be rare. We present the case of a 25-year-old male with diffuse alveolar hemorrhage and myocarditis followed by atypical hemolytic uremic syndrome. In this case, successful treatments included...
متن کاملPulmonary thromboembolism and diffuse alveolar hemorrhage in granulomatosis with polyangiitis vasculitis.
Granulomatosis with polyangiitis (GPA) is a small-vessel and medium-vessel vasculitis that affects mainly the respiratory tract and kidney. The main acute complications of GPA are diffuse pulmonary hemorrhage and acute renal failure. Renal involvement occurs in 17% of patients, with histological features of pauci-immune, focal, and segmental necrotizing crescentic glomerulonephritis.1 Diffuse a...
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ژورنال
عنوان ژورنال: Military Medicine
سال: 2006
ISSN: 0026-4075,1930-613X
DOI: 10.7205/milmed.171.8.781